Medical and Cell Biology Research

【烈冰助力】单细胞核测序+空间组学，烈冰生物助力重医附一院神经内科团队解析抑郁行为发生新机制

根据世界卫生组织（WHO）的数据，自2017年以来，重度抑郁症（MDD）已成为世界上最主要的残疾原因之一，其潜在的细胞和分子机制已有研究者对于男性的MDD基于单细胞分辨率进行初步探索（Corina Nagy, Nat Neurosci 2020）。本研究为首次基于单细胞核测序技术（snRNA-Seq

2023-07-26

【烈冰助力】单细胞技术揭示肿瘤细胞驱动的免疫逃逸机制

近日，烈冰合作伙伴上海质子重离子医院孔琳教授团队在Nature Communications（IF=17.694）上发表了题为“Tumor-intrinsic YTHDF1 drives immune evasion and resistance to immune checkpoint inhib

2023-03-31

Li H, et al. Characterization of differentially expressed genes involved in pathways associated with gastric cancer. PLoS One. 2015 Apr 30;10(4):e0125013. (IF= 3.234)

胃癌相关信号通路中的基因表达差异-瑞金医院

2015-04-01

Cai Z, et al. Transcriptomic analysis of hepatic responses to testosterone deficiency in miniature pigs fed a high-cholesterol diet. BMC Genomics. 2015 Feb 6;16:59. (IF=4.041)

高胆固醇摄入猪的睾酮缺乏脂肪肝转录组分析-浙江中医药大学

2015-02-01

Liu R, et al. DNMT1-microRNA126 epigenetic circuit contributes to esophageal squamous cell carcinoma growth via ADAM9-EGFR-AKT signaling. Clin Cancer Res. 2015 Feb 15;21(4):854-63. (IF=8.193)

食管鳞状细胞癌发生发展的分子机制研究-复旦大学

2015-02-01

Xu, T.,et al. High-throughput RNA sequencing reveals the effects of 2,2′,4,4′ -tetrabromodiphenyl ether on retina and bone development of zebrafish larvae. BMC Genomics.2015 Jan;16(1):23.(IF=3.729)

RNA-Seq揭示四溴二苯醚对斑马鱼视网膜和骨骼发育的影响-同济大学

2015-01-01

Jiao Y, et al. Long intergenic non‑coding RNA induced by X‑ray irradiation regulates DNA damage response signaling in the human bronchial epithelial BEAS‑2B cell line. Oncol Lett. 2015 Jan;9(1):169-176. (IF=0.987)

lncRNA参与X射线辐射造成支气管上皮细胞DNA损伤的分子机制-苏州大学

2015-01-01

Sun S, et al. Targeting the c-Met/FZD8 signaling axis eliminates patient-derived cancer stem-like cells in head and neck squamous carcinomas. Cancer Res. 2014 Dec 15;74(24):7546-59. (IF=9.284)

头颈鳞癌的生物标志物研究-上海交通大学附属第九人民医院

2014-12-01

Hu S, et al. Transcriptomic changes during the pre-receptive to receptive transition in human endometrium detected by RNA-Seq. J Clin Endocrinol Metab. 2014 Dec;99(12):E2744-53. (IF=6.49)

子宫内膜接受能力的基因表达研究-上海交大医学院附属仁济医院

2014-12-01

in Z, et al. Genome-wide screening and co-expression network analysis identify recurrence-specific biomarkers of esophageal squamous cell carcinoma. Tumor Biol. 2014 Nov;35(11):10959-68. (IF=2.84)

食管鳞状细胞癌共表达网络分析-复旦大学中山医院

2014-11-01

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